INT222981

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.62
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (TGFB1, MMRN1) aging (TGFB1) enzyme binding (TGFB1)
embryo development (TGFB1) cytoplasm (TGFB1) extracellular space (TGFB1)
TGFB1 (Homo sapiens)
MMRN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 21 96.24 Very High Very High Very High
Inflammation 19 95.84 Very High Very High Very High
Chronic pancreatitis 33 77.84 Quite High
fibrosis 8 50.00 Quite Low
chemokine 5 19.16 Low Low
Pain 2 10.76 Low Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 77 99.80 Very High Very High Very High
Fibrosis 21 99.72 Very High Very High Very High
INFLAMMATION 20 95.84 Very High Very High Very High
Cirrhosis 7 92.96 High High
Pancreatitis 33 77.84 Quite High
Stress 1 76.80 Quite High
Injury 2 58.48 Quite High
Necrosis 1 44.00 Quite Low
Apoptosis 2 43.64 Quite Low
Complex Regional Pain Syndromes 2 11.12 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TGFbeta was subsequently confirmed as a key regulator of ECM production and PSC proliferation due to its inhibition of MMPs in an autocrine fashion which enhanced fibrogenesis by reducing collagen degradation [23].
TGFbeta Positive_regulation (regulator) of Gene_expression (production) of ECM associated with fibrosis and primary sclerosing cholangitis
1) Confidence 0.09 Published 2007 Journal J Transl Med Section Body Doc Link PMC2234395 Disease Relevance 1.62 Pain Relevance 0.25

General Comments

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