INT222986

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTPRC)
Anatomy Link Frequency
mononuclear cell 1
PTPRC (Homo sapiens)
SMN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 33 98.06 Very High Very High Very High
cytokine 21 75.92 Quite High
Inflammation 19 50.00 Quite Low
fibrosis 8 50.00 Quite Low
chemokine 5 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 77 99.12 Very High Very High Very High
Pancreatitis 33 98.06 Very High Very High Very High
Fibrosis 21 50.00 Quite Low
INFLAMMATION 20 50.00 Quite Low
Sepsis 15 5.00 Very Low Very Low Very Low
Cirrhosis 7 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Complex Regional Pain Syndromes 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To judge the pattern of extracellular matrix protein distribution within and in the vicinity of mononuclear cell infiltrates in human chronic pancreatitis tissues (n = 10), immunohistochemistry was performed with antibodies against mononuclear cells (CD45; MNC), activated pancreatic stellate cells (alpha smooth muscle actin, alpha-SMA; vimentin; activated PSC), and the ECM proteins fibronectin and collagen1.
CD45 Positive_regulation (activated) of alpha-SMA in mononuclear cell associated with primary sclerosing cholangitis and chronic pancreatitis
1) Confidence 0.01 Published 2007 Journal J Transl Med Section Body Doc Link PMC2234395 Disease Relevance 0.46 Pain Relevance 0.26

General Comments

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