INT223040

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (AR) transport (AR) enzyme binding (AR)
DNA binding (AR) cell-cell signaling (AR) cytoplasm (AR)
Anatomy Link Frequency
EPI 2
AR (Homo sapiens)
TFPI (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 4 100.00 Very High Very High Very High
agonist 16 75.96 Quite High
antagonist 9 29.68 Quite Low
Catecholamine 7 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
antinociception 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 8 5.00 Very Low Very Low Very Low
Aids-related Complex 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Leukemia 1 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
2A-AR signal causing loss of UK14,304 potency (-Log EC50 (M): Vehicle 6.9 ± 0.2; EPI 6.3 ± 0.2) and efficacy (Imax (%): Vehicle 68.2 ± 5.4; EPI 49.3 ± 10.4; p < 0.05; Fig. 3B).
AR Positive_regulation (causing) of Negative_regulation (loss) of EPI in EPI associated with potency
1) Confidence 0.03 Published 2007 Journal BMC Pharmacol Section Body Doc Link PMC2234403 Disease Relevance 0 Pain Relevance 0.13

General Comments

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