INT223056

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Context Info
Confidence 0.22
First Reported 2007
Last Reported 2007
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ADRBK1) signal transduction (ADRBK1) aging (ADRBK1)
plasma membrane (ADRBK1) cytoplasm (ADRBK1)
Anatomy Link Frequency
SH-SY5Y 2
EPI 2
ADRBK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Catecholamine 14 98.64 Very High Very High Very High
Potency 8 21.40 Low Low
antagonist 18 6.84 Low Low
agonist 32 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
antinociception 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 16 5.00 Very Low Very Low Very Low
Aids-related Complex 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic EPI exposure altered neither GRK3 nor GRK2 levels in the transfected SH-SY5Y cell line (Table 4).
Neg (neither) Regulation (altered) of Neg (neither) Gene_expression (levels) of GRK2 in SH-SY5Y
1) Confidence 0.22 Published 2007 Journal BMC Pharmacol Section Body Doc Link PMC2234403 Disease Relevance 0 Pain Relevance 0.05
Chronic EPI exposure does not alter GRK2 or GRK3 levels in whole cells but instead enhances GRK2 and GRK3 expression at the membrane in SH?
Neg (not) Regulation (alter) of Gene_expression (levels) of GRK2 in EPI
2) Confidence 0.22 Published 2007 Journal BMC Pharmacol Section Body Doc Link PMC2234403 Disease Relevance 0 Pain Relevance 0.07

General Comments

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