INT223081

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.07
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Pdgfb) cytoplasm (Pdgfb)
Anatomy Link Frequency
vasculature 2
Pdgfb (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 2 98.68 Very High Very High Very High
Inflammation 74 92.60 High High
Arthritis 58 73.96 Quite High
Potency 2 29.60 Quite Low
imagery 20 5.00 Very Low Very Low Very Low
cytokine 16 5.00 Very Low Very Low Very Low
rheumatoid arthritis 16 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 3 98.88 Very High Very High Very High
Experimental Melanoma 7 94.64 High High
Arthritis 84 93.80 High High
Targeted Disruption 98 93.12 High High
INFLAMMATION 52 92.60 High High
Solid Tumor 2 90.32 High High
Cancer 124 81.36 Quite High
Metastasis 4 66.64 Quite High
Necrosis 16 63.92 Quite High
Rheumatoid Arthritis 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
are mainly expressed in the developing vasculature, where PDGF-BB is produced by endothelial cells and PDGFR-?
Negative_regulation (where) of Gene_expression (produced) of PDGF-BB in vasculature
1) Confidence 0.37 Published 2007 Journal BMC Cancer Section Abstract Doc Link PMC2234427 Disease Relevance 0.62 Pain Relevance 0
Among more than 50 known angiogenic factors (including matrix metalloproteinases, adhesion molecules, enzymes, and growth factors), we found that expression levels of PDGF-B, PDGF receptor ?
Negative_regulation (levels) of Gene_expression (expression) of PDGF-B associated with metalloproteinase and adhesions
2) Confidence 0.33 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246237 Disease Relevance 1.23 Pain Relevance 0.24
Among more than 50 known angiogenic factors (including matrix metalloproteinases, adhesion molecules, enzymes, and growth factors), we found that expression levels of PDGF-B, PDGF receptor ?
Negative_regulation (levels) of Gene_expression (expression) of PDGF-B associated with metalloproteinase and adhesions
3) Confidence 0.33 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246237 Disease Relevance 1.23 Pain Relevance 0.24

General Comments

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