INT223082

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.25
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.14
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Pdgfrb) plasma membrane (Pdgfrb) nucleus (Pdgfrb)
kinase activity (Pdgfrb) lysosome (Pdgfrb) cytoplasm (Pdgfrb)
Pdgfrb (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 1 93.00 High High
cva 2 64.52 Quite High
isoflurane 4 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
pruritus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 209 98.16 Very High Very High Very High
Apoptosis 6 94.08 High High
Myeloid Leukemia 39 91.68 High High
Experimental Melanoma 14 87.68 High High
Gastrointestinal Stromal Tumor 4 85.28 High High
Disease 5 72.72 Quite High
Solid Tumor 4 67.92 Quite High
Leukemia 14 67.12 Quite High
Philadelphia Chromosome 12 66.92 Quite High
Pressure And Volume Under Development 4 64.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Together, these examples suggest potential benefits of targeting PDGFR-?
Regulation (targeting) of PDGFR
1) Confidence 0.25 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2234427 Disease Relevance 0.69 Pain Relevance 0.03
The function of BCR-ABL has allowed the design and development of imatinib, a small-molecule kinase inhibitor that targets PDGFR, c-Kit, and ABL kinases (Deininger et al 2005).
Regulation (targets) of PDGFR
2) Confidence 0.18 Published 2008 Journal OncoTargets and therapy Section Body Doc Link PMC2994207 Disease Relevance 1.11 Pain Relevance 0.05
The crucial importance of PDGF-B and PDGFR-?
Regulation (importance) of PDGFR
3) Confidence 0.11 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2234427 Disease Relevance 0.34 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox