INT223089

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Context Info
Confidence 0.26
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lysosome (IDS, NAGLU) hydrolase activity, acting on glycosyl bonds (NAGLU)
IDS (Homo sapiens)
NAGLU (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 2 88.72 High High
Antihistamine 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
carpal tunnel syndrome 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 43 90.64 High High
Death 8 80.92 Quite High
Congenital Anomalies 6 69.04 Quite High
Cleidocranial Dysplasia 5 65.44 Quite High
Coronary Heart Disease 3 64.44 Quite High
Airway Obstruction 6 54.88 Quite High
Apnoea 3 53.96 Quite High
Tracheomalacia 2 51.44 Quite High
Lysosome Storage Disease 8 50.00 Quite Low
Mucopolysaccharidosis Ii 7 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The recent introduction of enzyme replacement therapy (ERT) with recombinant human I2S (idursulfase), however, has raised the possibility that the burden of GAG storage can be reduced and that the progressive tissue and organ damage associated with MPS II can be slowed or even prevented.
idursulfase Binding (associated) of MPS II
1) Confidence 0.26 Published 2007 Journal Eur J Pediatr Section Body Doc Link PMC2234442 Disease Relevance 0.72 Pain Relevance 0.09

General Comments

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