INT223278

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Context Info
Confidence 0.44
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.35
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TERT) DNA binding (TERT) cytoplasm (TERT)
RNA binding (TERT) chromosome (TERT) nucleolus (TERT)
Anatomy Link Frequency
nodules 2
TERT (Homo sapiens)
Pain Link Frequency Relevance Heat
transdermal 15 9.20 Low Low
depression 13 5.00 Very Low Very Low Very Low
antidepressant 4 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
psychological dependence 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Prolactinoma 1 100.00 Very High Very High Very High
Reprotox - General 1 29 99.78 Very High Very High Very High
Residual Neoplasm 2 98.24 Very High Very High Very High
Erythrocytosis 10 94.92 High High
Fistula 1 93.36 High High
Lower Urinary Tract Symptoms 6 93.24 High High
Benign Prostatic Hypertrophy 9 91.88 High High
Frailty 4 87.92 High High
Apnoea 8 85.76 High High
Prostate Cancer 2 82.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A small group of professionals, mainly specialists, raised concerns regarding practice regulation; they considered that in some instances TCs intervene above their abilities:

"There should be a regulation regarding the interventions that the TCs can perform; some perform surgery above their capacities, for example: fistulas, prostate cancer, etc.

Positive_regulation (instances) of TCs Binding (intervene) of associated with fistula and reprotox - general 1
1) Confidence 0.44 Published 2007 Journal Hum Resour Health Section Body Doc Link PMC2235883 Disease Relevance 0.19 Pain Relevance 0
The presence of breast cancer is also a contraindication for TRT as well as a prolactinoma, as their growth may be stimulated by HRT.26 Very high risk of serious adverse outcomes, undiagnosed prostate nodules or indurations, unexplained PSA elevation, erythrocytosis (hematocrit > 50%), severe lower urinary tract symptoms with benign prostatic hyperplasia with an International Prostate Symptom Score (IPSS) >19, and unstable congestive heart failure (class III or IV), untreated obstructive sleep apnea are considered as moderate- to high-risk factors for potential adverse outcomes.26,45,319

Conclusion

Positive_regulation (stimulated) of TRT Binding (contraindication) of in nodules associated with apnoea, benign prostatic hypertrophy, erythrocytosis, prolactinoma, frailty, lower urinary tract symptoms and reprotox - general 1
2) Confidence 0.34 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2701485 Disease Relevance 1.16 Pain Relevance 0

General Comments

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