INT22329

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Context Info
Confidence 0.66
First Reported 1990
Last Reported 2010
Negated 7
Speculated 0
Reported most in Body
Documents 36
Total Number 38
Disease Relevance 15.84
Pain Relevance 1.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptprc)
Anatomy Link Frequency
leukocytes 5
LSEC 3
R1-2 2
bone marrow 2
neutrophil 2
Ptprc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
imagery 33 99.60 Very High Very High Very High
abdominal pain 7 96.60 Very High Very High Very High
ischemia 42 96.16 Very High Very High Very High
Paracetamol 3 95.68 Very High Very High Very High
Inflammation 91 91.68 High High
vincristine 2 91.60 High High
cytokine 68 85.28 High High
fibrosis 9 82.08 Quite High
backache 1 75.68 Quite High
corticosteroid 3 68.48 Quite High
Disease Link Frequency Relevance Heat
Hemangioma 112 100.00 Very High Very High Very High
Cancer 461 99.76 Very High Very High Very High
Recurrence 365 99.48 Very High Very High Very High
Myocardial Infarction 51 98.40 Very High Very High Very High
Rectal Cancer 396 97.88 Very High Very High Very High
Splenomegaly 6 97.76 Very High Very High Very High
Adhesions 17 96.64 Very High Very High Very High
Abdominal Pain 7 96.60 Very High Very High Very High
Cv Unclassified Under Development 43 96.16 Very High Very High Very High
Hypersplenism 4 95.96 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cells were positive for leukocyte common antigen (LCA) and showed finely vacuolated basophilic cytoplasm in both the peripheral blood smear and bone marrow biopsy, characteristic of Burkitt's lymphoma cells.
Gene_expression (positive) of LCA in leukocyte associated with lymphatic system cancer
1) Confidence 0.66 Published 1990 Journal J. Korean Med. Sci. Section Abstract Doc Link 2278668 Disease Relevance 1.03 Pain Relevance 0.06
Immunohistochemistry confirmed that in vivo expression of CD45 in LSEC had a lobular distribution with enhanced CD45 staining in periportal LSEC.
Gene_expression (ession of ) of CD45 in LSEC
2) Confidence 0.60 Published 2010 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 20813915 Disease Relevance 0.50 Pain Relevance 0.14
Three subpopulations of LSEC were isolated by immunomagnetic separation on the basis of CD45 expression.
Gene_expression (expression) of CD45 in LSEC
3) Confidence 0.60 Published 2010 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 20813915 Disease Relevance 0.57 Pain Relevance 0.08
In conclusion, CD45 is highly expressed in periportal LSEC, low in midlobular LSEC, and negative in centrilobular LSEC, and this provides an easy separation method to isolate LSEC from the three different hepatic regions.
Neg (negative) Gene_expression (essed in ) of CD45 in LSEC
4) Confidence 0.60 Published 2010 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 20813915 Disease Relevance 0.13 Pain Relevance 0.10
For example, the RT prescription may affect the results.
Gene_expression (prescription) of RT
5) Confidence 0.54 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.26 Pain Relevance 0
LCA may also present with a myriad of possible signs and symptoms, such as: splenomegaly with or without abdominal pain, hypersplenism with ensuing anaemia and/or thrombocytopenia, and constitutional symptoms such as intermittent fevers.
Gene_expression (present) of LCA associated with abdominal pain, anaemia, splenomegaly, hemangioma, thrombocytopenia, hypersplenism and fever
6) Confidence 0.50 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2527567 Disease Relevance 2.18 Pain Relevance 0.15
Pooled results of trials comparing preoperative RT to surgery alone
Gene_expression (preoperative) of RT
7) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.10 Pain Relevance 0.06
After surgery, patients at high risk of local recurrence (T4 stage, R1-2 or intraoperative tumor perforation) also received 41.4 Gy if they had preoperative RT and 59.8 Gy if they did not have preoperative RT.
Gene_expression (preoperative) of RT in R1-2 associated with cancer and recurrence
8) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.50 Pain Relevance 0
Preoperative RT alone versus preoperative RT plus chemotherapy
Gene_expression (alone) of RT
9) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.54 Pain Relevance 0
Preoperative RT was better in reducing local recurrence rates and was associated with lower morbidity.
Gene_expression (was) of RT associated with recurrence
10) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.46 Pain Relevance 0
Preoperative RT versus surgery alone
Gene_expression (Preoperative) of RT
11) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.11 Pain Relevance 0
Preoperative RT alone versus preoperative RT plus chemotherapy
Gene_expression (alone) of RT
12) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.54 Pain Relevance 0
Results were expressed as relative risk ratios (RR) with 95% confidence intervals (CI), where a RR less than 1.0 favors preoperative RT and a RR greater than 1.0 favors surgery alone.
Gene_expression (expressed) of RT
13) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.35 Pain Relevance 0
After surgery, patients at high risk of local recurrence (T4 stage, R1-2 or intraoperative tumor perforation) also received 41.4 Gy if they had preoperative RT and 59.8 Gy if they did not have preoperative RT.
Gene_expression (preoperative) of RT in R1-2 associated with cancer and recurrence
14) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.51 Pain Relevance 0
Should preoperative RT be recommended for adjuvant treatment in resectable rectal cancer?
Gene_expression (preoperative) of RT associated with rectal cancer
15) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.49 Pain Relevance 0
Preoperative RT versus alternative treatments
Gene_expression (Preoperative) of RT
16) Confidence 0.47 Published 2003 Journal BMC Med Section Body Doc Link PMC281590 Disease Relevance 0.80 Pain Relevance 0
The expression of these molecular markers has also been demonstrated in fine-needle aspiration biopsies of LCA [33].
Gene_expression (expression) of LCA associated with hemangioma
17) Confidence 0.45 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2527567 Disease Relevance 1.29 Pain Relevance 0
Infiltration of CD45+ leukocytes and T cell subpopulations
Gene_expression (leukocytes) of CD45 in T cell
18) Confidence 0.32 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2956665 Disease Relevance 0.08 Pain Relevance 0
As shown in Figure 2, the total amount of CD45+ leukocytes did not vary between both allogeneic groups.
Gene_expression (leukocytes) of CD45 in leukocytes
19) Confidence 0.32 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2956665 Disease Relevance 0.29 Pain Relevance 0
Immunofluorescence staining showed that MSCs expressed the mesenchymal cell marker CD29 (Figure 1B), but did not express hematopoietic stem cell markers CD34 or CD45.
Neg (not) Gene_expression (express) of CD45 in hematopoietic stem cell
20) Confidence 0.28 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2905634 Disease Relevance 0 Pain Relevance 0.05

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