INT223323

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Context Info
Confidence 0.67
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.03
Pain Relevance 1.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SNRNP70) mRNA processing (SNRNP70) RNA binding (SNRNP70)
nucleus (SNRNP70)
Anatomy Link Frequency
adipocyte 1
SNRNP70 (Homo sapiens)
SNRNP70 - A1032G (1)
Pain Link Frequency Relevance Heat
Calcium channel 10 99.46 Very High Very High Very High
Analgesic 71 99.10 Very High Very High Very High
aspirin 19 98.64 Very High Very High Very High
Pain score 7 97.94 Very High Very High Very High
Pain 14 97.34 Very High Very High Very High
Arthritis 43 89.16 High High
noradrenaline 5 79.12 Quite High
cytokine 1 79.04 Quite High
agonist 12 75.44 Quite High
rheumatoid arthritis 6 69.84 Quite High
Disease Link Frequency Relevance Heat
Asthma 65 98.96 Very High Very High Very High
Pain 24 97.80 Very High Very High Very High
Obesity 132 92.80 High High
Occupational Lung Diseases 7 89.72 High High
Juvenile Chronic Polyarthritis 35 89.16 High High
Hypersensitivity 3 89.16 High High
Arthritis 8 87.04 High High
Necrosis 1 82.80 Quite High
Cancer 1 82.44 Quite High
Disorder Of Lipid Metabolism 5 77.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Relation of ESR1 SNPs and mRNA levels to adipocyte lipolysis and lipogenesis phenotypes
Transcription (levels) of SNP in adipocyte
1) Confidence 0.67 Published 2007 Journal BMC Med Genet Section Body Doc Link PMC2238734 Disease Relevance 0.83 Pain Relevance 0.11
We also found that the SNP, rs17810546, which lies 5?
Transcription (found) of SNP
2) Confidence 0.22 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC3002762 Disease Relevance 0.80 Pain Relevance 0.30
Patients who experie</span>nced more severe pain, evaluated by NRS pain scores, required higher-dose and more frequent rescue analgesics, although significant associations were not observed between the A1032G SNP or ?
Neg (not) Transcription (observed) of A1032G SNP (A1032G) associated with pain, pain score and analgesic
3) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2738941 Disease Relevance 0.35 Pain Relevance 1.06
AIA: aspirin-intolerant asthma; ATA: aspirin-tolerant asthma; CACNG6: calcium channel: voltage-dependent: gamma subunit 6; SNP: single nucleotide polymorphism; MAF: minor allele frequency; LD: linkage disequilibrium; OR: odds ratio; CI: confidence interval

Competing interests

Transcription (subunit 6) of SNP associated with asthma, aspirin and calcium channel
4) Confidence 0.04 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2954844 Disease Relevance 1.05 Pain Relevance 0.24

General Comments

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