INT223331

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GGT5) plasma membrane (GGT5) transferase activity, transferring acyl groups (GGT5)
cellular amino acid metabolic process (GGT5)
GGT5 (Homo sapiens)
Pain Link Frequency Relevance Heat
antidepressant 73 82.08 Quite High
depression 57 80.92 Quite High
methotrexate 1 28.44 Quite Low
sSRI 9 5.00 Very Low Very Low Very Low
noradrenaline 7 5.00 Very Low Very Low Very Low
tricyclic antidepressant 6 5.00 Very Low Very Low Very Low
fluoxetine 5 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
anticonvulsant 3 5.00 Very Low Very Low Very Low
Serotonin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 61 80.92 Quite High
Disease 6 26.68 Quite Low
Mental Disorders 12 5.00 Very Low Very Low Very Low
Adverse Drug Reaction 7 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 7 5.00 Very Low Very Low Very Low
Psychosis 4 5.00 Very Low Very Low Very Low
Depressive Disorder 3 5.00 Very Low Very Low Very Low
Suicidal Behaviour 3 5.00 Very Low Very Low Very Low
Recurrence 3 5.00 Very Low Very Low Very Low
Cardiovascular Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With this in mind, the following 7 (out of the possible 27) genes in the folate pathway will be investigated in the first instance:

• methylenetetrahydrofolate reductase • thymidylate synthase • dihydrofolate reductase • methionine synthase • methionine synthase reductase • gamma glutamyl hydrolase • reduced folate carrier (SLC19A1).

Negative_regulation (reductase) of Gene_expression (reductase) of gamma glutamyl
1) Confidence 0.03 Published 2007 Journal BMC Psychiatry Section Body Doc Link PMC2238748 Disease Relevance 0.08 Pain Relevance 0.08

General Comments

This test has worked.

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