INT223372

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Context Info
Confidence 0.58
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.03
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (HSPA1B) cytosol (HSPA1B) mitochondrion (HSPA1B)
endoplasmic reticulum (HSPA1B) nucleus (HSPA1B) response to stress (HSPA1B)
HSPA1B (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 11 50.12 Quite High
Inflammation 23 49.72 Quite Low
chemokine 3 47.56 Quite Low
Substantia nigra 8 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
cocaine 3 5.00 Very Low Very Low Very Low
vincristine 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 5 100.00 Very High Very High Very High
Disease 92 96.86 Very High Very High Very High
Infection 47 92.40 High High
Necrosis 2 55.80 Quite High
Cancer 13 55.44 Quite High
Francisella Infection 58 50.00 Quite Low
Diabetes Mellitus 5 50.00 Quite Low
INFLAMMATION 29 49.72 Quite Low
Sprains And Strains 38 32.60 Quite Low
Injury 1 7.48 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Relative gene expression of four genes (Bcl6, Traf2 binding protein, heat shock protein 1B, and Cytochrome P450) was measured by qRTPCR.
Gene_expression (expression) of heat shock protein 1B associated with shock
1) Confidence 0.58 Published 2010 Journal BMC Infect Dis Section Body Doc Link PMC2826305 Disease Relevance 0.71 Pain Relevance 0.03
Thirty-one priority genes have been previously designated PD candidate genes (http://www.pdgene.org/) (SI_Table_1f), and it is worth noting that 33 are considered AD candidate genes as well (SI_Table_1g) with HSPA1A, HSPA1B, HTR2A, KCNJ6, SLC6A3, SNCA, SNCG, TF and UCHL1 being present in both lists.
Gene_expression (present) of HSPA1B associated with disease
2) Confidence 0.43 Published 2008 Journal Neurogenetics Section Body Doc Link PMC2238789 Disease Relevance 0.33 Pain Relevance 0

General Comments

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