INT223523

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Context Info
Confidence 0.21
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hmga1) molecular_function (Erv4) enzyme binding (Hmga1)
cellular_component (Erv4) transcription factor binding (Hmga1) biological_process (Erv4)
Hmga1 (Mus musculus)
Erv4 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 8 40.48 Quite Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Burns 91 100.00 Very High Very High Very High
Sepsis 2 87.20 High High
Hematological Disease 1 76.76 Quite High
Pathologic Processes 1 75.24 Quite High
Stress 13 56.12 Quite High
Disease 7 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Demyelinating Disease 4 5.00 Very Low Very Low Very Low
Autoimmune Disease 4 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We can speculate that the elevated systemic levels of HMGA1 protein during burn-elicited septic development may enhance transcriptional activities of certain MuERV U3 promoters, such as K-4-5 U3, K-4-10 U3, L-4-3 U3, and U-4-1 U3, through the HMGA1/1 binding element.
Positive_regulation (levels) of HMGA1 Spec (may) Positive_regulation (enhance) of MuERV U3 associated with burns
1) Confidence 0.21 Published 2007 Journal BMC Genomics Section Body Doc Link PMC2241634 Disease Relevance 0.95 Pain Relevance 0

General Comments

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