INT223549

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Context Info
Confidence 1.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cnr2) plasma membrane (Cnr2) signal transducer activity (Cnr2)
Anatomy Link Frequency
brain 1
Cnr2 (Mus musculus)
Pain Link Frequency Relevance Heat
Cannabinoid 13 91.28 High High
alcohol 25 89.28 High High
drug abuse 11 84.88 Quite High
Intracerebroventricular 6 84.32 Quite High
depression 36 84.28 Quite High
agonist 20 57.68 Quite High
antagonist 18 56.64 Quite High
Pain 2 14.24 Low Low
cocaine 6 5.00 Very Low Very Low Very Low
qutenza 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Dependence 14 84.88 Quite High
Depression 37 84.28 Quite High
Alcohol Addiction 5 76.40 Quite High
Autoimmune Disease 1 30.64 Quite Low
Osteoporosis 1 29.64 Quite Low
Sleep Disorders 1 23.04 Low Low
Catalepsy 1 22.00 Low Low
Pain 2 14.24 Low Low
Stress 32 5.00 Very Low Very Low Very Low
Sprains And Strains 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We then hypothesized that if CB2-Rs are present in the brain, then antisense oligonucleotides complementary to CB2 mRNA transcript will block translation of or stimulate degradation of CB2 mRNA.
Protein_catabolism (degradation) of CB2 in brain
1) Confidence 1.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2241668 Disease Relevance 0.72 Pain Relevance 0.54

General Comments

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