INT223581

Context Info Confidence 0.00 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.47 Pain Relevance 0

nucleus (TXK, DBP) plasma membrane (TXK) DNA binding (TXK) cytoplasm (TXK)

TXK (Homo sapiens) DBP (Homo sapiens)

Pain Link Frequency Relevance Heat addiction 1 5.00 nud 1 5.00 headache 1 5.00

Disease Link Frequency Relevance Heat Advanced Or Metastatic Breast Cancer 11 95.52 Cancer 26 83.48 Immunotherapy Of Cancer 3 78.28 Breast Cancer 30 69.28 Disease 17 5.00 Vomiting 5 5.00 Diarrhoea 3 5.00 Endometriosis (extended) 3 5.00 Toxicity 2 5.00 Hyperglycemia 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Gefitinib and erlotinib are small molecule tyrosine kinase inhibitors of the ATP binding site of EGFR and have been shown to delay the development of tamoxifen resistance in vitro [18].

small molecule tyrosine kinase Negative_regulation (inhibitors) of ATP binding site

1) Confidence 0.00 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2242654 Disease Relevance 0.47 Pain Relevance 0

General Comments

This test has worked.