INT223825

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Context Info
Confidence 0.11
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.53
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (GSTP1, MAPK8) cytosol (GSTP1, MAPK8) nucleus (GSTP1, MAPK8)
nucleoplasm (MAPK8) mitochondrion (MAPK8) small molecule metabolic process (GSTP1)
GSTP1 (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
dorsal root ganglion 4 63.24 Quite High
induced neuropathy 2 48.08 Quite Low
tolerance 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 10 94.48 High High
Stress 4 87.56 High High
Drug Induced Neurotoxicity 32 77.12 Quite High
Dysesthesia 26 65.52 Quite High
Ganglion Cysts 4 63.24 Quite High
Cancer 10 50.44 Quite High
Testicular Cancer 22 50.00 Quite Low
Neuropathic Pain 2 48.08 Quite Low
Stomach Cancer 2 46.52 Quite Low
Leukemia 6 17.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hypothetically, protection against cisplatin-induced toxicities might be due to less effective JNK inactivation by the GSTP1-G-derived enzyme GSTP1105Val.
GSTP1 Negative_regulation (inactivation) of JNK
1) Confidence 0.11 Published 2007 Journal J Transl Med Section Body Doc Link PMC2245909 Disease Relevance 0.77 Pain Relevance 0.03
Hypothetically, protection against cisplatin-induced toxicities might be due to less effective JNK inactivation by the GSTP1-G-derived enzyme GSTP1105Val.
GSTP1-G-derived Negative_regulation (inactivation) of JNK
2) Confidence 0.07 Published 2007 Journal J Transl Med Section Body Doc Link PMC2245909 Disease Relevance 0.76 Pain Relevance 0.03

General Comments

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