INT223827

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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.88
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (MAPK8, GSTP1) cytosol (MAPK8, GSTP1) nucleus (MAPK8, GSTP1)
nucleoplasm (MAPK8) mitochondrion (MAPK8) small molecule metabolic process (GSTP1)
MAPK8 (Homo sapiens)
GSTP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
dorsal root ganglion 2 74.84 Quite High
induced neuropathy 1 59.68 Quite High
tolerance 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 2 99.58 Very High Very High Very High
Apoptosis 5 98.84 Very High Very High Very High
Drug Induced Neurotoxicity 16 88.72 High High
Dysesthesia 13 77.12 Quite High
Ganglion Cysts 2 74.84 Quite High
Cancer 5 62.04 Quite High
Neuropathic Pain 1 59.68 Quite High
Stomach Cancer 1 58.12 Quite High
Testicular Cancer 11 50.00 Quite Low
Leukemia 3 28.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Oxidative stress releases GSTP1 from JNK, which in turn activates the expression of GSTP1 and other genes involved in apoptosis and cytoprotection [39].
JNK Positive_regulation (activates) of Gene_expression (expression) of GSTP1 associated with stress and apoptosis
1) Confidence 0.12 Published 2007 Journal J Transl Med Section Body Doc Link PMC2245909 Disease Relevance 0.88 Pain Relevance 0.10

General Comments

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