INT223828

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.80
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (GSTP1, MAPK8) cytosol (GSTP1, MAPK8) nucleus (GSTP1, MAPK8)
nucleoplasm (MAPK8) mitochondrion (MAPK8) small molecule metabolic process (GSTP1)
GSTP1 (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
dorsal root ganglion 4 80.16 Quite High
induced neuropathy 2 65.00 Quite High
tolerance 2 9.44 Low Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 4 100.00 Very High Very High Very High
Apoptosis 10 97.90 Very High Very High Very High
Drug Induced Neurotoxicity 32 94.04 High High
Dysesthesia 26 82.44 Quite High
Ganglion Cysts 4 80.16 Quite High
Cancer 10 67.36 Quite High
Neuropathic Pain 2 65.00 Quite High
Stomach Cancer 2 63.44 Quite High
Testicular Cancer 22 50.00 Quite Low
Leukemia 6 34.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alteration of intracellular apoptosis pathways might represent an alternative or additional explanation to varying detoxification efficacies: GSTP1 monomers bind- and thus inactivate the stress-inducible Jun N-terminal kinase (JNK) [38].
GSTP1 Spec (might) Binding (bind) of JNK associated with stress and apoptosis
1) Confidence 0.06 Published 2007 Journal J Transl Med Section Body Doc Link PMC2245909 Disease Relevance 0.90 Pain Relevance 0.11
Alteration of intracellular apoptosis pathways might represent an alternative or additional explanation to varying detoxification efficacies: GSTP1 monomers bind- and thus inactivate the stress-inducible Jun N-terminal kinase (JNK) [38].
GSTP1 Spec (might) Binding (bind) of Jun N-terminal kinase associated with stress and apoptosis
2) Confidence 0.06 Published 2007 Journal J Transl Med Section Body Doc Link PMC2245909 Disease Relevance 0.90 Pain Relevance 0.11

General Comments

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