INT223863

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Context Info
Confidence 0.31
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mapk1) mitochondrion (Mapk1) protein complex (Mapk1)
cytoplasm (Mapk1) cytosol (Mapk1) signal transduction (Mapk1)
Mapk1 (Mus musculus)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 104 100.00 Very High Very High Very High
Anterior cingulate cortex 34 99.68 Very High Very High Very High
nMDA receptor 14 51.68 Quite High
Hippocampus 9 20.88 Low Low
Action potential 6 5.00 Very Low Very Low Very Low
Lasting pain 4 5.00 Very Low Very Low Very Low
Pyramidal cell 3 5.00 Very Low Very Low Very Low
amygdala 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 6 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we demonstrated that ERK activation is required for the induction of LTP in the ACC and that the MEK inhibitors did not affect the maintenance phase of cingulate LTP.
Positive_regulation (activation) of ERK Positive_regulation (required) of Positive_regulation (induction) of LTP associated with long-term potentiation and anterior cingulate cortex
1) Confidence 0.31 Published 2007 Journal Mol Pain Section Body Doc Link PMC2245920 Disease Relevance 0 Pain Relevance 0.43

General Comments

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