INT223875

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Context Info
Confidence 0.31
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 1.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk8) signal transduction (Mapk8) mitochondrion (Mapk8)
nucleus (Mapk8) kinase activity (Mapk8) cytoplasm (Mapk8)
Mapk8 (Mus musculus)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 312 100.00 Very High Very High Very High
Anterior cingulate cortex 102 95.52 Very High Very High Very High
Pyramidal cell 9 74.08 Quite High
Hippocampus 27 45.52 Quite Low
nMDA receptor 42 44.72 Quite Low
Action potential 18 34.72 Quite Low
Lasting pain 12 5.00 Very Low Very Low Very Low
amygdala 6 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 18 5.00 Very Low Very Low Very Low
Pain 15 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibitors of c-Jun N-terminal kinase (JNK) and p38 also suppressed the induction of cingulate LTP generated by the pairing protocol.
Negative_regulation (Inhibitors) of c-Jun N-terminal kinase Negative_regulation (suppressed) of Positive_regulation (induction) of LTP associated with long-term potentiation
1) Confidence 0.31 Published 2007 Journal Mol Pain Section Body Doc Link PMC2245920 Disease Relevance 0 Pain Relevance 0.34
Furthermore, we showed that inhibitors of other members of MAPK family, such as JNK and p38, also blocked the induction of cingulate LTP generated by the pairing protocol.
Negative_regulation (inhibitors) of JNK Negative_regulation (blocked) of Positive_regulation (induction) of LTP associated with long-term potentiation
2) Confidence 0.23 Published 2007 Journal Mol Pain Section Body Doc Link PMC2245920 Disease Relevance 0 Pain Relevance 0.38
Inhibitors of c-Jun N-terminal kinase (JNK) and p38 also suppressed the induction of cingulate LTP generated by the pairing protocol.
Negative_regulation (Inhibitors) of JNK Negative_regulation (suppressed) of Positive_regulation (induction) of LTP associated with long-term potentiation
3) Confidence 0.23 Published 2007 Journal Mol Pain Section Body Doc Link PMC2245920 Disease Relevance 0 Pain Relevance 0.34

General Comments

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