INT223954

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.70
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bglap) cytoplasm (Bglap)
Bglap (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 8 97.88 Very High Very High Very High
Chronic pancreatitis 36 96.88 Very High Very High Very High
fibrosis 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 58 99.12 Very High Very High Very High
Pancreatitis 36 96.88 Very High Very High Very High
Adenocarcinoma 62 96.74 Very High Very High Very High
Calcification 2 77.28 Quite High
Metastasis 10 70.20 Quite High
Disease 4 67.28 Quite High
Breast Cancer 4 64.96 Quite High
Cancer 30 62.76 Quite High
Adhesions 2 61.24 Quite High
Reprotox - General 1 2 58.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
was able to moderately but consistently reduce BGLAP mRNA and protein levels in the four cultured pancreatic cancer cell lines (figure 6A &6B).
Negative_regulation (reduce) of Transcription (levels) of BGLAP associated with pancreatic cancer
1) Confidence 0.41 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2245975 Disease Relevance 0.96 Pain Relevance 0.09
As the cellular composition of bulk PDAC and CP tissues is different than that of normal pancreatic tissues, BGLAP mRNA values were normalized to amylase-2A (Amy2A) mRNA levels for each tissue sample to exclude the mRNA expression of BGLAP in the acini (figure 1B).
Negative_regulation (exclude) of Transcription (expression) of BGLAP associated with adenocarcinoma and chronic pancreatitis
2) Confidence 0.41 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2245975 Disease Relevance 1.73 Pain Relevance 0.40

General Comments

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