INT224021

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PIK3CG, EPHB2) cytosol (PIK3CG) cytoplasm (PIK3CG)
PIK3CG (Homo sapiens)
EPHB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 1 99.18 Very High Very High Very High
noradrenaline 9 78.64 Quite High
Inflammatory response 1 47.20 Quite Low
metalloproteinase 2 6.24 Low Low
Inflammation 21 5.00 Very Low Very Low Very Low
antagonist 19 5.00 Very Low Very Low Very Low
adenocard 13 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
Migraine 8 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 24 69.12 Quite High
Disease 12 65.60 Quite High
Diabetes Mellitus 11 64.72 Quite High
Cardiovascular Disease 11 63.28 Quite High
Increased Venous Pressure Under Development 61 62.32 Quite High
INFLAMMATION 21 46.80 Quite Low
Neointima 5 45.68 Quite Low
Adhesions 4 21.52 Low Low
Sepsis 1 7.08 Low Low
Myocardial Infarction 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The signal transduction is mediated via Gq proteins, phospholipase C and D, diacylglycerol, protein kinase C, extracellular signal-regulated kinase, phosphatidylinositol-3 kinase, MAPK/ERK activity kinase, mitogen-activated protein kinases and Rho [12, 128, 129].
phosphatidylinositol-3 kinase Negative_regulation (kinase) of ERK associated with kinase c
1) Confidence 0.03 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245998 Disease Relevance 0.50 Pain Relevance 0.09

General Comments

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