INT22403

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.39
First Reported 1990
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 10
Total Number 11
Disease Relevance 2.50
Pain Relevance 1.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (MSMB) extracellular region (MSMB) nucleus (MSMB)
molecular_function (MSMB) biological_process (MSMB)
Anatomy Link Frequency
plasma 3
neurons 2
HGF 1
PSP 1
MSMB (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain threshold 4 97.56 Very High Very High Very High
opioid receptor 1 94.00 High High
metalloproteinase 1 93.36 High High
Inflammation 8 91.96 High High
withdrawal 5 89.36 High High
chemokine 1 89.04 High High
Endogenous opioid 1 87.92 High High
Glutamate 4 85.12 High High
imagery 6 84.96 Quite High
Enkephalin 2 82.16 Quite High
Disease Link Frequency Relevance Heat
Disease 27 99.76 Very High Very High Very High
Death 8 99.52 Very High Very High Very High
Prostate Cancer 100 98.32 Very High Very High Very High
Pain 10 97.56 Very High Very High Very High
INFLAMMATION 8 92.32 High High
Metastasis 52 92.20 High High
Starvation 1 87.04 High High
Benign Prostatic Hypertrophy 115 82.80 Quite High
Mental Disorders 7 80.76 Quite High
Injury 3 68.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An MSP outreach unit was therefore established and staffed by people experienced in occupational health and familiar with key organizations, primarily labor unions representing responders.


Regulation (staffed) of MSP
1) Confidence 0.39 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1764159 Disease Relevance 0.08 Pain Relevance 0
STUDY DESIGN: A prospective cohort study in which alterations in MSP symptoms were documented over a two-year period.
Regulation (alterations) of MSP
2) Confidence 0.23 Published 2004 Journal Int J Circumpolar Health Section Body Doc Link 15736681 Disease Relevance 0.09 Pain Relevance 0
Additional highly expressed, androgen-regulated genes included KLK3 (PSA), MSMB (beta-microseminoprotein), ACPP (prostatic acid phosphatase) and SCGB1A1 (uteroglobin).


Regulation (regulated) of MSMB
3) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2793011 Disease Relevance 0.37 Pain Relevance 0.24
Changes in plasma beta-EP, serum cortisol, circulating nutritional markers, and their relative levels were assessed on the 5th and 10th days of fasting, and on the 5th and 10th days of the refeeding period.
Regulation (Changes) of plasma beta-EP in plasma
4) Confidence 0.21 Published 1990 Journal Horm. Res. Section Abstract Doc Link 2289782 Disease Relevance 0.09 Pain Relevance 0.09
MSMB, CCND1, EFNA3, FKBP and ADM, HGF are similarly regulated in mouse models and in our study [35-37].
Regulation (regulated) of MSMB in HGF
5) Confidence 0.18 Published 2007 Journal BMC Cancer Section Body Doc Link PMC1865555 Disease Relevance 0.69 Pain Relevance 0.04
Although some control groups with PRPs (Group B and C) showed higher BMC and BMD values compared to the group grafted with ?
Regulation (control) of PRPs
6) Confidence 0.14 Published 2010 Journal The Journal of Advanced Prosthodontics Section Body Doc Link PMC2984511 Disease Relevance 0.16 Pain Relevance 0.09
The MSP neurons themselves are also differentially affected.
Regulation (affected) of MSP in neurons
7) Confidence 0.09 Published 1999 Journal Prog. Neurobiol. Section Abstract Doc Link 10845758 Disease Relevance 0.38 Pain Relevance 0.19
Medium spiny projection (MSP) neurons are the first striatal cells to be affected as the disease progresses whilst interneurons, in particular the NADPH diaphorase positive ones, are spared even in the late stages of the disease.
Regulation (affected) of MSP in neurons associated with disease
8) Confidence 0.09 Published 1999 Journal Prog. Neurobiol. Section Abstract Doc Link 10845758 Disease Relevance 0.37 Pain Relevance 0.12
Unfortunately the PSP decay time ?
Regulation (Unfortunately) of PSP in PSP
9) Confidence 0.03 Published 2008 Journal Cogn Neurodyn Section Body Doc Link PMC2585619 Disease Relevance 0 Pain Relevance 0.15
This study investigated whether the circadian oscillation in plasma melatonin is involved in the modulation of plasma beta-END immunoreactivity (beta-END-ir), and whether fluctuations in pain threshold measured using the hotplate test are contingent upon the fluctuation of these two hormones in Rattus Norvegicus.
Spec (whether) Regulation (modulation) of plasma beta-END in plasma associated with pain threshold
10) Confidence 0.01 Published 2000 Journal Life Sci. Section Abstract Doc Link 10794063 Disease Relevance 0.26 Pain Relevance 0.36
CONCLUSION: The combination of small dose of ketamine with morphine provides optimal analgesia with low side-effect rate and little effect on the plasma beta-EP level.


Neg (little) Regulation (effect) of plasma beta-EP in plasma
11) Confidence 0.01 Published 2009 Journal Zhonghua Yi Xue Za Zhi Section Body Doc Link 19563707 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox