INT224049

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 5.12
Pain Relevance 1.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adora2b) plasma membrane (Adora2b) signal transducer activity (Adora2b)
Anatomy Link Frequency
urinary bladder 1
caecum 1
large intestine 1
Adora2b (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 397 99.88 Very High Very High Very High
adenocard 357 99.68 Very High Very High Very High
Spinal cord 6 92.56 High High
antagonist 73 88.32 High High
Inflammation 85 84.76 Quite High
ischemia 190 79.92 Quite High
hypoalgesia 3 79.08 Quite High
Hyperalgesia 3 59.08 Quite High
Neurotransmitter 4 56.08 Quite High
Thalamus 6 50.08 Quite High
Disease Link Frequency Relevance Heat
Hypoxia 32 98.74 Very High Very High Very High
Disease 22 95.20 Very High Very High Very High
Alzheimer's Dementia 3 93.52 High High
Toxicity 3 92.56 High High
Obesity 13 89.52 High High
INFLAMMATION 80 84.76 Quite High
Cv Unclassified Under Development 187 83.60 Quite High
Hypoalagesia 3 79.08 Quite High
Aggression 3 78.44 Quite High
Increased Venous Pressure Under Development 21 75.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with previous work showing selective A2BAR induction with vascular hypoxia [24] or myocardial IP [28], these studies reveal induction of A2BAR transcript and protein with renal IP treatment.


Transcription (transcript) of A2BAR associated with hypoxia
1) Confidence 0.69 Published 2008 Journal PLoS Medicine Section Body Doc Link PMC2504049 Disease Relevance 0.28 Pain Relevance 0.06
These studies revealed prompt and selective induction of the A2BAR transcript following renal IP (approximately 6-fold induction 60 min after IP, p < 0.05, Figure 9C).
Transcription (transcript) of A2BAR
2) Confidence 0.69 Published 2008 Journal PLoS Medicine Section Body Doc Link PMC2504049 Disease Relevance 0.27 Pain Relevance 0.08
Principally as a result of the difficulty in identifying potent and selective agonists, the A2B AR is the least extensively characterised of the adenosine receptors family.
Transcription (characterised) of A2B associated with adenocard and agonist
3) Confidence 0.42 Published 2008 Journal Purinergic Signal Section Abstract Doc Link PMC2583210 Disease Relevance 0.14 Pain Relevance 0.36
In the periphery, high levels of A2BR were detected in the caecum, large intestine and urinary bladder.
Transcription (detected) of A2BR in large intestine
4) Confidence 0.24 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 1.48 Pain Relevance 0.40
In the periphery, high levels of A2BR were detected in the caecum, large intestine and urinary bladder.
Transcription (detected) of A2BR in urinary bladder
5) Confidence 0.08 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 1.48 Pain Relevance 0.40
In the periphery, high levels of A2BR were detected in the caecum, large intestine and urinary bladder.
Transcription (detected) of A2BR in caecum
6) Confidence 0.08 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 1.48 Pain Relevance 0.40

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox