INT224087

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adrbk1) aging (Adrbk1) plasma membrane (Adora2a)
enzyme binding (Adora2a) signal transducer activity (Adora2a) cytoplasm (Adrbk1)
Adrbk1 (Rattus norvegicus)
Adora2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 60 99.28 Very High Very High Very High
agonist 103 84.60 Quite High
antagonist 17 28.88 Quite Low
Inflammation 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Thalamus 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Cannabinoid 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 11 67.28 Quite High
Necrosis 1 66.72 Quite High
Disease 6 5.00 Very Low Very Low Very Low
Hypoxia 5 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Neuroblastoma 4 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 3 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 3 5.00 Very Low Very Low Very Low
Bordatella Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This was probably caused by GRK2-dependent pre-desensitization of the A2AR by extracellular adenosine.
GRK2 Negative_regulation (desensitization) of A2AR associated with adenocard
1) Confidence 0.10 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 0.13 Pain Relevance 0.22

General Comments

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