INT224102

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.19
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.44
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adrbk1) aging (Adrbk1) cytoplasm (Adrbk1)
Anatomy Link Frequency
plasma 4
Adrbk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 309 89.28 High High
adenocard 180 88.96 High High
antagonist 51 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
Spinal cord 6 5.00 Very Low Very Low Very Low
Thalamus 6 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
Cannabinoid 6 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 3 90.16 High High
Cancer 33 89.80 High High
Leukemia 3 83.28 Quite High
Disease 18 5.00 Very Low Very Low Very Low
Hypoxia 15 5.00 Very Low Very Low Very Low
Obesity 12 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Neuroblastoma 12 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 9 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
treatment prevented GRK2 translocation to and decreased GRK2 association with the plasma membranes of these cells as a consequence of the activation of a sphingomyelinase-dependent pathway.
Negative_regulation (prevented) of Localization (translocation) of GRK2 in plasma
1) Confidence 0.19 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 0.18 Pain Relevance 0.25
An inhibitor of MAPK activation (PD98059) also caused inhibition of A3R phosphorylation, desensitization and internalization, probably by preventing the membrane translocation of GRK2.
Negative_regulation (preventing) of Localization (translocation) of GRK2
2) Confidence 0.14 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 0.08 Pain Relevance 0.11
treatment prevented GRK2 translocation to and decreased GRK2 association with the plasma membranes of these cells as a consequence of the activation of a sphingomyelinase-dependent pathway.
Negative_regulation (decreased) of Localization (translocation) of GRK2 in plasma
3) Confidence 0.14 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 0.18 Pain Relevance 0.25

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox