INT224130

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Adora2a, ADCY1) small molecule metabolic process (ADCY1) GTPase activity (ADCY1)
enzyme binding (Adora2a) transmembrane transport (ADCY1) signal transducer activity (Adora2a)
Anatomy Link Frequency
NG108-15 2
Adora2a (Rattus norvegicus)
ADCY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 103 90.68 High High
adenocard 60 86.96 High High
antagonist 17 34.96 Quite Low
Inflammation 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Thalamus 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Cannabinoid 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 11 55.68 Quite High
Necrosis 1 55.12 Quite High
Disease 6 5.00 Very Low Very Low Very Low
Hypoxia 5 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Neuroblastoma 4 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 3 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 3 5.00 Very Low Very Low Very Low
Bordatella Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The acute stimulation of adenylyl cyclase by activation of A2AR was markedly reduced in NG108-15 cells overexpressing wild-type GRK2.
Positive_regulation (activation) of A2AR in NG108-15 Positive_regulation (stimulation) of adenylyl cyclase
1) Confidence 0.01 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 0.11 Pain Relevance 0.22

General Comments

This test has worked.

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