INT224135

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ARRB2, Adora2b) cytosol (ARRB2) signal transduction (Adora2b)
cytoplasmic membrane-bounded vesicle (ARRB2) nucleus (ARRB2) signal transducer activity (Adora2b)
ARRB2 (Homo sapiens)
Adora2b (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 103 93.80 High High
antagonist 17 79.56 Quite High
adenocard 60 50.00 Quite Low
Inflammation 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Thalamus 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Cannabinoid 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaplastic Astrocytoma 3 66.56 Quite High
Cancer 11 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Hypoxia 5 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Neuroblastoma 4 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 3 5.00 Very Low Very Low Very Low
Bordatella Infection 2 5.00 Very Low Very Low Very Low
Skin Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One explanation for this may be a higher affinity of the A2BR for arrestin 2 compared to arrestin 3.
arrestin 3 Binding (affinity) of A2BR
1) Confidence 0.14 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 0.07 Pain Relevance 0.23

General Comments

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