INT22426

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Context Info
Confidence 0.48
First Reported 1990
Last Reported 2005
Negated 1
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.33
Pain Relevance 1.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrna2) plasma membrane (Chrna2)
Anatomy Link Frequency
muscle 2
Chrna2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 8 100.00 Very High Very High Very High
antagonist 1 100.00 Very High Very High Very High
Morphine 4 98.88 Very High Very High Very High
addiction 3 97.72 Very High Very High Very High
Nicotine 3 93.56 High High
tetrodotoxin 4 92.44 High High
withdrawal 1 91.68 High High
Disease Link Frequency Relevance Heat
Paralysis 3 92.84 High High
Opiate Addiction 1 91.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that neither muscle activity nor innervation alone, but a combination of both, is required for full regulation of AChR antigenicity.
Neg (nor) Positive_regulation (required) of Regulation (regulation) of AChR in muscle
1) Confidence 0.48 Published 1990 Journal Neurosci. Lett. Section Abstract Doc Link 2293108 Disease Relevance 0.24 Pain Relevance 0.32
Effects of alpha4beta2 and alpha7 nicotinic acetylcholine receptor antagonists on place aversion induced by naloxone in single-dose morphine-treated rats.
Positive_regulation (induced) of Regulation (Effects) of nicotinic acetylcholine receptor associated with antagonist, narcan and morphine
2) Confidence 0.44 Published 2005 Journal Eur. J. Pharmacol. Section Title Doc Link 16098507 Disease Relevance 0.09 Pain Relevance 1.00

General Comments

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