INT224285

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (BDNF) nucleolus (Trib3) nucleus (Trib3)
cytoplasmic membrane-bounded vesicle (BDNF) enzyme binding (Trib3) kinase activity (Trib3)
BDNF (Homo sapiens)
Trib3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Sciatic nerve 68 78.56 Quite High
Spinal cord 89 78.40 Quite High
bDMF 213 72.48 Quite High
Central nervous system 12 38.76 Quite Low
Dorsal column 13 5.00 Very Low Very Low Very Low
halothane 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Peripheral nerve injury 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sciatic Neuropathy 32 78.56 Quite High
Spinal Cord Injury 37 78.40 Quite High
Injury 32 19.92 Low Low
Nervous System Injury 9 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Contusions 5 5.00 Very Low Very Low Very Low
Overdose 4 5.00 Very Low Very Low Very Low
Paralysis 2 5.00 Very Low Very Low Very Low
Vibrio Infection 2 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Most recently it was discovered that neurotrophins activated extracellular signal-regulated kinase (Erk) in a Trk-dependent way and activated Erk inhibited phosphodiesterase-4 (PDE4).
neurotrophin Positive_regulation (activated) of kinase
1) Confidence 0.06 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2246162 Disease Relevance 0.22 Pain Relevance 0.36

General Comments

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