INT224290

Context Info Confidence 0.17 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0

nucleoplasm (ESR1, CCND1) enzyme binding (ESR1, CCND1) cytoplasm (ESR1, CCND1) nucleus (ESR1, CCND1) intracellular (CCND1) DNA binding (ESR1)

ESR1 (Homo sapiens) CCND1 (Homo sapiens)

Pain Link Frequency Relevance Heat agonist 9 5.00 antagonist 4 5.00 Potency 2 5.00 addiction 1 5.00 Pain 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Reprotox - General 1 5 65.84 Breast Cancer 33 50.00 Apoptosis 26 5.00 Death 4 5.00 Cancer 4 5.00 Endometriosis (extended) 2 5.00 Leukemia 2 5.00 Pain 1 5.00 Sarcoma 1 5.00 Bacterial Respiratory Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Interestingly, the estrogen-stimulated induction of the cyclin D1 mRNA level was decreased by decursin only at the 3 hour timepoint.

estrogen Positive_regulation (induction) of cyclin D1 mRNA

1) Confidence 0.17 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2246173 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.