INT224302

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Context Info
Confidence 0.26
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (PSEN2) endoplasmic reticulum (PSEN2) embryo development (PSEN2)
protein complex (PSEN2) cytosol (PSEN2) peptidase activity (PSEN2)
PSEN2 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 6 28.32 Quite Low
agonist 18 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Rsd 6 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 13 79.44 Quite High
Breast Cancer 66 50.00 Quite Low
Reprotox - General 1 10 34.16 Quite Low
Apoptosis 52 5.00 Very Low Very Low Very Low
Death 8 5.00 Very Low Very Low Very Low
Cancer 8 5.00 Very Low Very Low Very Low
Reflex Sympathetic Dystrophy 6 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Leukemia 4 5.00 Very Low Very Low Very Low
Endometriosis (extended) 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and pS2 mRNA levels were not decreased by decursinol treatment (Figure 5c, lanes 7 and 8 versus lane 2).
Neg (not) Negative_regulation (decreased) of Transcription (levels) of pS2
1) Confidence 0.26 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2246173 Disease Relevance 0 Pain Relevance 0
mRNA level, the pS2 mRNA level was only modestly decreased by decursin or DA.
Negative_regulation (decreased) of Transcription (level) of pS2
2) Confidence 0.19 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2246173 Disease Relevance 0 Pain Relevance 0
Positions corresponding to pB, pS1 and pS2 transcription start sites are shown

The pS1 and pS2 promoters are negatively regulated by ppGpp and DksA in vitro

Negative_regulation (sites) of Transcription (transcription) of pS2
3) Confidence 0.04 Published 2010 Journal Mol Genet Genomics Section Body Doc Link PMC2939334 Disease Relevance 0.08 Pain Relevance 0

General Comments

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