INT224306

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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (KDR, VEGFA) extracellular region (KDR, VEGFA) extracellular space (VEGFA)
growth (VEGFA) proteinaceous extracellular matrix (VEGFA) nucleus (KDR)
KDR (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 57.76 Quite High
cytokine 2 20.56 Low Low
methotrexate 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 106 75.04 Quite High
INFLAMMATION 3 57.76 Quite High
Breast Cancer 42 53.64 Quite High
Malignant Neoplastic Disease 2 30.00 Quite Low
Hypoxia 18 27.76 Quite Low
Disease 4 10.40 Low Low
Advanced Or Metastatic Breast Cancer 6 5.00 Very Low Very Low Very Low
Metastasis 4 5.00 Very Low Very Low Very Low
Solid Tumor 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The neuropilins bind not only class 3 semaphorins, which are involved in axonal growth, but also some isoforms of VEGF, where they function as co-receptors, increasing VEGF binding to VEGFR2 [86].
VEGFR2 Positive_regulation (increasing) of VEGF
1) Confidence 0.24 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2246178 Disease Relevance 0.36 Pain Relevance 0.03

General Comments

This test has worked.

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