INT224398

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.71
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (UROD) small molecule metabolic process (UROD) lyase activity (UROD)
nucleolus (UROD) nucleus (UROD) cytoplasm (UROD)
Anatomy Link Frequency
thymocyte 1
UROD (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 1 79.12 Quite High
Inflammation 10 73.32 Quite High
ischemia 4 65.16 Quite High
cytokine 3 23.96 Low Low
anesthesia 6 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bacterial Infection 21 98.84 Very High Very High Very High
Sepsis 30 88.08 High High
Disease 1 85.88 High High
Respiratory Distress 3 84.88 Quite High
Asphyxia 1 79.92 Quite High
Cv General 3 Under Development 1 79.12 Quite High
Pneumothorax 1 77.12 Quite High
INFLAMMATION 12 73.32 Quite High
Infection 42 69.40 Quite High
Cv Unclassified Under Development 4 65.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Key messages

• The type of immunosuppressive therapy influences procalcitonin (PCT) serum levels in liver transplant patients. • Administration of anti-thymocyte globulin (ATG) is a powerful stimulus for PCT synthesis and release. • The transient high PCT values in orthotopic liver transplantation patients with and without ATG treatment are not caused by bacterial infection. • There is still limited knowledge on the mechanisms of PCT synthesis and release.


Localization (release) of PCT associated with bacterial infection
1) Confidence 0.49 Published 2007 Journal Crit Care Section Body Doc Link PMC2246230 Disease Relevance 0.35 Pain Relevance 0.09
Key messages

• The type of immunosuppressive therapy influences procalcitonin (PCT) serum levels in liver transplant patients. • Administration of anti-thymocyte globulin (ATG) is a powerful stimulus for PCT synthesis and release. • The transient high PCT values in orthotopic liver transplantation patients with and without ATG treatment are not caused by bacterial infection. • There is still limited knowledge on the mechanisms of PCT synthesis and release.


Localization (release) of PCT in thymocyte associated with bacterial infection
2) Confidence 0.49 Published 2007 Journal Crit Care Section Body Doc Link PMC2246230 Disease Relevance 0.55 Pain Relevance 0.13
PCT and CRP decrease to their normal values after 2-3 days and 3-7 days, respectively [23-25].
Localization (decrease) of PCT
3) Confidence 0.20 Published 2010 Journal BMC Pediatr Section Body Doc Link PMC3016366 Disease Relevance 0.82 Pain Relevance 0.04

General Comments

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