INT224403

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCK) extracellular space (CCK) extracellular region (CCK)
plasma membrane (GYPC)
Anatomy Link Frequency
plasma 1
stomach 1
CCK (Homo sapiens)
GYPC (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 186 100.00 Very High Very High Very High
antagonist 14 94.56 High High
Morphine 4 5.00 Very Low Very Low Very Low
Versed 4 5.00 Very Low Very Low Very Low
spastic colon 2 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Critical Illness 76 96.36 Very High Very High Very High
Appetite Loss 4 73.68 Quite High
Eating Disorder 4 72.24 Quite High
Attention Deficit Hyperactivity Disorder 2 62.20 Quite High
Hepatotoxicity 2 45.92 Quite Low
Diabetes Mellitus 2 37.20 Quite Low
Sleep Disorders 8 5.00 Very Low Very Low Very Low
Sepsis 8 5.00 Very Low Very Low Very Low
Obesity 6 5.00 Very Low Very Low Very Low
Functional Bowel Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study was designed to examine the following hypotheses: (a) slow GE is associated with elevated plasma concentrations of CCK and PYY, and (b) GE is a determinant of postprandial concentrations of CCK and PYY in the critically ill.


CCK Binding (associated) of GE in plasma associated with critical illness and cholecystokinin
1) Confidence 0.04 Published 2007 Journal Crit Care Section Body Doc Link PMC2246231 Disease Relevance 0.63 Pain Relevance 0.33
In healthy humans, exogenous administration of CCK and PYY is associated with relaxation of the proximal stomach, inhibition of antral motor activity, stimulation of contractions localised to the pylorus, slowing of GE [1,2,4,7,11,12], and a reduction in energy intake [3,4,13-16].
CCK Binding (associated) of GE in stomach associated with cholecystokinin
2) Confidence 0.04 Published 2007 Journal Crit Care Section Body Doc Link PMC2246231 Disease Relevance 0.20 Pain Relevance 0.44

General Comments

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