INT224404

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.48
Pain Relevance 1.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (PYY) extracellular space (PYY) extracellular region (PYY)
plasma membrane (GYPC) cytoskeleton organization (PYY) cell-cell signaling (PYY)
Anatomy Link Frequency
plasma 2
stomach 1
GYPC (Homo sapiens)
PYY (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 279 100.00 Very High Very High Very High
antagonist 21 96.00 Very High Very High Very High
spastic colon 3 94.68 High High
nud 3 93.32 High High
Opioid 3 41.16 Quite Low
Morphine 6 5.00 Very Low Very Low Very Low
Versed 6 5.00 Very Low Very Low Very Low
Neuropeptide 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Critical Illness 114 99.46 Very High Very High Very High
Functional Bowel Disorder 3 94.68 High High
Dyspepsia 3 93.32 High High
Appetite Loss 6 73.68 Quite High
Eating Disorder 6 72.24 Quite High
Attention Deficit Hyperactivity Disorder 3 62.20 Quite High
Hypoglycemia 3 53.20 Quite High
Hepatotoxicity 3 46.56 Quite Low
Diabetes Mellitus 3 37.84 Quite Low
Sleep Disorders 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In healthy humans, exogenous administration of CCK and PYY is associated with relaxation of the proximal stomach, inhibition of antral motor activity, stimulation of contractions localised to the pylorus, slowing of GE [1,2,4,7,11,12], and a reduction in energy intake [3,4,13-16].
GE Binding (associated) of PYY in stomach associated with cholecystokinin
1) Confidence 0.04 Published 2007 Journal Crit Care Section Body Doc Link PMC2246231 Disease Relevance 0.20 Pain Relevance 0.44
During critical illness, the relationship between GE, plasma CCK, and PYY is complex.
GE Binding (complex) of PYY in plasma associated with critical illness and cholecystokinin
2) Confidence 0.04 Published 2007 Journal Crit Care Section Body Doc Link PMC2246231 Disease Relevance 0.65 Pain Relevance 0.65
This study was designed to examine the following hypotheses: (a) slow GE is associated with elevated plasma concentrations of CCK and PYY, and (b) GE is a determinant of postprandial concentrations of CCK and PYY in the critically ill.


GE Binding (associated) of PYY in plasma associated with critical illness and cholecystokinin
3) Confidence 0.04 Published 2007 Journal Crit Care Section Body Doc Link PMC2246231 Disease Relevance 0.63 Pain Relevance 0.33

General Comments

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