INT224414

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2010
Negated 2
Speculated 2
Reported most in Body
Documents 15
Total Number 17
Disease Relevance 11.75
Pain Relevance 1.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plaque 1
lumen 1
common carotid artery 1
CIMT (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 276 99.82 Very High Very High Very High
Inflammation 99 98.88 Very High Very High Very High
imagery 31 96.24 Very High Very High Very High
tolerance 21 95.28 Very High Very High Very High
alcohol 7 57.08 Quite High
cva 9 48.76 Quite Low
Angina 19 38.00 Quite Low
depression 6 28.56 Quite Low
agonist 26 5.00 Very Low Very Low Very Low
Bile 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 58 100.00 Very High Very High Very High
Rheumatoid Arthritis 279 99.82 Very High Very High Very High
Hyperlipoproteinemia Type Ii 150 99.32 Very High Very High Very High
Disorder Of Lipid Metabolism 496 99.20 Very High Very High Very High
INFLAMMATION 100 98.88 Very High Very High Very High
Stroke 150 98.84 Very High Very High Very High
Cv General 4 Under Development 32 98.40 Very High Very High Very High
Atherosclerosis 248 97.96 Very High Very High Very High
Hemiplegia 34 96.48 Very High Very High Very High
Disease 132 95.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ultrasound images were frozen by ECG triggering (top of R-wave) to minimize variability depending on changes in the cIMT and lumen diameter occurring during the cardiac cycle [7,17].
Regulation (changes) of cIMT in lumen
1) Confidence 0.39 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246234 Disease Relevance 0.44 Pain Relevance 0.09
After addition of RA as an interactive term to the regression analysis, the presence of RA did not affect the relationship between age and cIMT.
Neg (not) Regulation (affect) of cIMT associated with rheumatoid arthritis
2) Confidence 0.39 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246234 Disease Relevance 1.47 Pain Relevance 0.53
Patients with RA had significantly higher average cIMT values and more plaque than the control group (cIMT 0.64 ± 0.13 mm versus 0.58 ± 0.09 mm, respectively; P = 0.03).
Regulation (values) of cIMT in plaque associated with rheumatoid arthritis
3) Confidence 0.23 Published 2007 Journal Arthritis Res Ther Section Abstract Doc Link PMC2246234 Disease Relevance 2.06 Pain Relevance 0.53
This study aims to compare the efficacy of CIMT to BIM training to improve outcomes across the ICF for school children with congenital hemiplegia.


Regulation (efficacy) of CIMT associated with hemiplegia
4) Confidence 0.21 Published 2010 Journal BMC Neurol Section Abstract Doc Link PMC2832893 Disease Relevance 0.48 Pain Relevance 0
We identified six randomised placebo-controlled studies that measured the effect of B-vitamin treatment on CIMT.
Regulation (effect) of CIMT
5) Confidence 0.17 Published 2008 Journal BMC Cardiovasc Disord Section Body Doc Link PMC2559819 Disease Relevance 0.09 Pain Relevance 0
Ours is the first study to investigate the effects of B-vitamin supplementation on FMD and CIMT in people with a history of stroke and TIA.
Spec (investigate) Regulation (effects) of CIMT associated with cv general 4 under development and stroke
6) Confidence 0.17 Published 2008 Journal BMC Cardiovasc Disord Section Body Doc Link PMC2559819 Disease Relevance 0.54 Pain Relevance 0
We did not find any significant differences in the effect of B-vitamins on CIMT or FMD among the etiological subtypes of stroke.
Regulation (effect) of CIMT associated with stroke
7) Confidence 0.17 Published 2008 Journal BMC Cardiovasc Disord Section Body Doc Link PMC2559819 Disease Relevance 0.10 Pain Relevance 0
We also conducted a systematic review and meta-analysis of studies designed to test the effect of B-vitamin treatment on CIMT and FMD.


Regulation (effect) of CIMT
8) Confidence 0.17 Published 2008 Journal BMC Cardiovasc Disord Section Abstract Doc Link PMC2559819 Disease Relevance 0.31 Pain Relevance 0
The final CIMT values for each subject were calculated as the mean of six measurements.
Regulation (values) of CIMT
9) Confidence 0.17 Published 2008 Journal BMC Cardiovasc Disord Section Body Doc Link PMC2559819 Disease Relevance 0.35 Pain Relevance 0.03
Furthermore, the propensity for progression may also have been altered, although its effect on CIMT outcomes in ENHANCE are difficult to determine.


Regulation (effect) of CIMT
10) Confidence 0.14 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988620 Disease Relevance 0.47 Pain Relevance 0
The Effect of Combination Ezetimibe and High-Dose Simvastatin vs Simvastatin Alone on the Atherosclerotic Process in Patients with Heterozygous Familial Hypercholesterolemia (ENHANCE) trial investigated the effects of therapy on CIMT in patients with heFH.40,77–86
Spec (investigated) Regulation (effects) of CIMT associated with atherosclerosis and hyperlipoproteinemia type ii
11) Confidence 0.08 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988620 Disease Relevance 0.60 Pain Relevance 0.05
The Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol-6-HDL and LDL Strategies in Atherosclerosis (ARBITER 6-HALTS) trial compared the effects on CIMT progression of extended-release NA, titrated to a daily dose of 2 g with that of 10 mg daily dose of ezetimibe in patients who were at target LDL-C levels (<2.6 mmol/L) as a result of statin therapy.87 NA cotherapy resulted in significant CIMT regression, whereas ezetimibe cotherapy had no significant effect on CIMT.
Neg (no) Regulation (effect) of CIMT associated with atherosclerosis and disorder of lipid metabolism
12) Confidence 0.08 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988620 Disease Relevance 0.31 Pain Relevance 0
The aim of the present study was to evaluate the association between serum PON-1 activities and CIMT values in patients with H. pylori.
Regulation (values) of CIMT
13) Confidence 0.08 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2936361 Disease Relevance 0.90 Pain Relevance 0
The change in mean CIMT for the rosuvastatin group for the common carotid artery sites was 0.0004 (95% CI, ?
Regulation (change) of CIMT in common carotid artery
14) Confidence 0.03 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2496987 Disease Relevance 0.24 Pain Relevance 0
The second purpose of this study was to assess the relationship between (a) CIMT and (b) endothelial function, IR and insulin sensitivity in this study population.


Regulation (sensitivity) of CIMT associated with insulin resistance
15) Confidence 0.03 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC2827804 Disease Relevance 2.40 Pain Relevance 0.10
The change in maximum CIMT for the 12 carotid sites was ?
Regulation (change) of CIMT
16) Confidence 0.03 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2672446 Disease Relevance 0.35 Pain Relevance 0.06
Despite significant favorable improvements in LDL and HDL in the torcetrapib/atorvastatin group, change in maximum CIMT was not significantly different in the torcetrapib/atorvastatin group (x = 0.025 mm/year) compared with the atorvastatin monotherapy group (x = 0.030 mm/year, P = 0.46).31
Regulation (change) of CIMT associated with disorder of lipid metabolism
17) Confidence 0.02 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.45 Pain Relevance 0.04

General Comments

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