INT224418

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Context Info
Confidence 0.11
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (NFKB2, TNFSF11) cell differentiation (TNFSF11) nucleoplasm (NFKB2)
intracellular (TNFSF11) extracellular matrix organization (NFKB2) DNA binding (NFKB2)
Anatomy Link Frequency
osteoblasts 1
NFKB2 (Homo sapiens)
TNFSF11 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 66 98.48 Very High Very High Very High
cytokine 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 66 98.48 Very High Very High Very High
Osteoporosis 16 90.20 High High
Hypercalcemia 7 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we explored in human OA subchondral bone whether chondroitin sulfate (CS), glucosamine sulfate (GS), or both together affect the major bone biomarkers, osteoprotegerin (OPG), receptor activator of nuclear factor-kappa B ligand (RANKL), and the pro-resorptive activity of OA osteoblasts.
nuclear factor-kappa B Binding (ligand) of RANKL in osteoblasts associated with osteoarthritis
1) Confidence 0.11 Published 2007 Journal Arthritis Res Ther Section Abstract Doc Link PMC2246236 Disease Relevance 0.68 Pain Relevance 0.30

General Comments

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