INT224442

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Context Info
Confidence 0.30
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.48
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pdgfa) extracellular region (Pdgfa)
Pdgfa (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 6 98.68 Very High Very High Very High
fibrosis 55 98.56 Very High Very High Very High
Inflammation 69 92.60 High High
Arthritis 29 73.96 Quite High
Kinase C 1 61.68 Quite High
Potency 1 30.08 Quite Low
cytokine 15 5.00 Very Low Very Low Very Low
rheumatoid arthritis 11 5.00 Very Low Very Low Very Low
imagery 10 5.00 Very Low Very Low Very Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 10 100.00 Very High Very High Very High
Adhesions 1 98.88 Very High Very High Very High
Internal Fibrosis 16 98.56 Very High Very High Very High
Arthritis 43 93.80 High High
Targeted Disruption 48 93.60 High High
Apoptosis 6 93.20 High High
INFLAMMATION 56 92.60 High High
Fibrosis 50 77.20 Quite High
Injury 11 68.80 Quite High
Metastasis 2 67.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among more than 50 known angiogenic factors (including matrix metalloproteinases, adhesion molecules, enzymes, and growth factors), we found that expression levels of PDGF-B, PDGF receptor ?
Negative_regulation (levels) of Gene_expression (expression) of PDGF associated with metalloproteinase and adhesions
1) Confidence 0.30 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246237 Disease Relevance 1.23 Pain Relevance 0.24
M inhibited PDGF-induced HSC proliferation, without any toxic effects.
Negative_regulation (inhibited) of Gene_expression (proliferation) of PDGF-induced associated with cirrhosis
2) Confidence 0.03 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2944211 Disease Relevance 1.25 Pain Relevance 0.26

General Comments

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