INT224449

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.72
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FBXO2) protein modification process (FBXO2) endoplasmic reticulum (FBXO2)
cytoplasm (FBXO2)
Anatomy Link Frequency
fat 2
FBXO2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 18 87.24 High High
Inflammation 82 86.84 High High
rheumatoid arthritis 16 61.16 Quite High
Arthritis 58 56.84 Quite High
imagery 20 50.72 Quite High
Potency 2 17.12 Low Low
tolerance 17 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 65 89.60 High High
Weight Loss 17 87.84 High High
INFLAMMATION 61 86.84 High High
Cancer 22 77.44 Quite High
Necrosis 18 74.16 Quite High
Targeted Disruption 97 72.88 Quite High
Breast Cancer 2 72.68 Quite High
Insulin Resistance 23 70.56 Quite High
Disorder Of Lipid Metabolism 9 62.52 Quite High
Rheumatoid Arthritis 16 61.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B in TNF-induced VEGF-C expression, we treated WT OCPs with an NF-?
Positive_regulation (treated) of Gene_expression (treated) of OCP
1) Confidence 0.49 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246237 Disease Relevance 0.55 Pain Relevance 0.03
To validate our microarray findings and provide insight into the mechanism of TNF-induced VEGF-C expression in OCPs, we provide preliminary evidence indicating that this response is mediated by NF-?
Positive_regulation (induced) of Gene_expression (expression) of OCP
2) Confidence 0.49 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246237 Disease Relevance 0.41 Pain Relevance 0.21
In both fat depots, fH gene expression was significantly higher than complement fB gene expression (Fig. 2).
Positive_regulation (higher) of Gene_expression (expression) of fH gene in fat
3) Confidence 0.01 Published 2010 Journal Diabetes Section Body Doc Link PMC2797922 Disease Relevance 0.76 Pain Relevance 0

General Comments

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