INT224453

Context Info Confidence 0.08 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.37 Pain Relevance 0.07

cytoplasm (Nfkb1, VEGFA) mitochondrion (Nfkb1) DNA binding (Nfkb1) protein complex (Nfkb1) cytosol (Nfkb1) signal transduction (Nfkb1)

Nfkb1 (Mus musculus) VEGFA (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 8 85.84 Potency 1 55.56 Inflammation 37 50.00 Arthritis 29 35.80 metalloproteinase 1 16.36 imagery 10 5.00 rheumatoid arthritis 8 5.00 Pain 1 5.00 Inflammatory mediators 1 5.00 psoriasis 1 5.00

Disease Link Frequency Relevance Heat Cancer 10 100.00 Necrosis 8 100.00 Targeted Disruption 48 88.28 Breast Cancer 1 85.12 Metastasis 2 37.44 Arthritis 42 35.80 Adhesions 1 16.76 INFLAMMATION 26 11.60 Rheumatoid Arthritis 8 5.00 Synovitis 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Nuclear factor-kappa B mediates tumor necrosis factor-induced VEGF-C expression

Nuclear factor-kappa B Positive_regulation (mediates) of Gene_expression (expression) of VEGF associated with necrosis and cancer

1) Confidence 0.08 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246237 Disease Relevance 0.37 Pain Relevance 0.07

General Comments

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