INT224461

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (F2RL1, CALCRL) signal transducer activity (F2RL1, CALCRL) protein transporter activity (CALCRL)
endosome (CALCRL) endoplasmic reticulum (CALCRL) Golgi apparatus (F2RL1)
Anatomy Link Frequency
endothelial cells 1
F2RL1 (Homo sapiens)
CALCRL (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 66 99.84 Very High Very High Very High
agonist 4 96.92 Very High Very High Very High
Bioavailability 1 55.52 Quite High
cytokine 11 39.20 Quite Low
metalloproteinase 24 5.00 Very Low Very Low Very Low
Inflammation 16 5.00 Very Low Very Low Very Low
COX2 3 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 67 99.84 Very High Very High Very High
Disease 5 17.60 Low Low
INFLAMMATION 15 5.00 Very Low Very Low Very Low
Hyperalgesia 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our finding that the PAR-2-AP, in addition to activating PAR-2, significantly upregulates the level of the receptor on OA chondrocytes agrees with a recent study showing that another PAR-2-AP agonist, 2-furoyl LIGKV-OH (ASK95), regulates the expression of PAR-2 in umbilical vein endothelial cells [18].
PAR-2-AP Positive_regulation (upregulates) of receptor in endothelial cells associated with agonist and osteoarthritis
1) Confidence 0.00 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246240 Disease Relevance 0.37 Pain Relevance 0.31

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox