INT224498

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Context Info
Confidence 0.26
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EPHB2)
Anatomy Link Frequency
chondrocytes 2
EPHB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 66 100.00 Very High Very High Very High
metalloproteinase 24 94.80 High High
cytokine 11 90.24 High High
Inflammation 16 69.56 Quite High
agonist 4 5.00 Very Low Very Low Very Low
COX2 3 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 67 100.00 Very High Very High Very High
INFLAMMATION 15 69.56 Quite High
Disease 5 5.00 Very Low Very Low Very Low
Hyperalgesia 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of PAR-2 activation on the phosphorylated levels of three MAP kinases of the OA chondrocytes (n = 3 to 4), namely Erk1/2, p38, and JNK, and on NF-?
Regulation (effect) of Positive_regulation (activation) of Erk1 in chondrocytes associated with osteoarthritis
1) Confidence 0.26 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246240 Disease Relevance 0.46 Pain Relevance 0.52

General Comments

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