INT224536

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Context Info
Confidence 0.45
First Reported 2007
Last Reported 2007
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.31
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ankh) plasma membrane (Ankh) molecular_function (Ankh)
cellular_component (Ankh) biological_process (Ankh)
Anatomy Link Frequency
chondrocytes 2
Ankh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 168 95.24 Very High Very High Very High
Osteoarthritis 8 67.20 Quite High
addiction 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Immobilon 4 5.00 Very Low Very Low Very Low
spinal inflammation 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chondrocalcinosis 48 96.66 Very High Very High Very High
Osteoarthritis 8 67.20 Quite High
Disease 12 59.68 Quite High
Aging 12 44.32 Quite Low
Repression 8 5.00 Very Low Very Low Very Low
Calcification 4 5.00 Very Low Very Low Very Low
Ankylosis 4 5.00 Very Low Very Low Very Low
Low Back Pain 4 5.00 Very Low Very Low Very Low
Cleidocranial Dysplasia 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
1-induced expression of Ank by Gö6976 was clearly dose-dependent and reached the control level at 10 ?
Regulation (dependent) of Gene_expression (expression) of Ank
1) Confidence 0.45 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0 Pain Relevance 0.32
However, neither the basal expression of Ank nor its induction by TGF-?
Neg (neither) Regulation (However) of Gene_expression (expression) of Ank
2) Confidence 0.45 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0.13 Pain Relevance 0.03
The siRNA technology was used to investigate the respective contributions of Ank and PC-1 on TGF-?
Spec (investigate) Regulation (respective) of Spec (investigate) Gene_expression (contributions) of Ank
3) Confidence 0.45 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0 Pain Relevance 0
1) was shown to favor calcium pyrophosphate dihydrate deposition, we investigated the contribution of ANK to the production of extracellular inorganic pyrophosphate (ePPi) by chondrocytes and the signaling pathways involved in the regulation of Ank expression by TGF-?
Regulation (regulation) of Gene_expression (expression) of Ank in chondrocytes associated with chondrocalcinosis
4) Confidence 0.27 Published 2007 Journal Arthritis Res Ther Section Abstract Doc Link PMC2246241 Disease Relevance 0.19 Pain Relevance 0

General Comments

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