INT224550

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Context Info
Confidence 0.43
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.73
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ankh) plasma membrane (Ankh) molecular_function (Ankh)
cellular_component (Ankh) biological_process (Ankh)
Anatomy Link Frequency
chondrocytes 1
synovial fluid 1
Ankh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 126 98.08 Very High Very High Very High
addiction 3 54.20 Quite High
Osteoarthritis 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
spinal inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 6 100.00 Very High Very High Very High
Chondrocalcinosis 36 99.78 Very High Very High Very High
Cancer 3 98.56 Very High Very High Very High
Cardiovascular Disease 3 98.12 Very High Very High Very High
Disease 9 30.56 Quite Low
Aging 9 5.00 Very Low Very Low Very Low
Osteoarthritis 6 5.00 Very Low Very Low Very Low
Calcification 3 5.00 Very Low Very Low Very Low
Ankylosis 3 5.00 Very Low Very Low Very Low
Low Back Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, probenecid was shown to inhibit Ank function [10] and TGF-?
Negative_regulation (inhibit) of Ank
1) Confidence 0.43 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0.37 Pain Relevance 0.07
1 signaling events may lead to insights in the field of sporadic chondrocalcinosis since the repression of Ank would translate into reduced ePPi levels in synovial fluid.
Negative_regulation (repression) of Ank in synovial fluid associated with chondrocalcinosis and repression
2) Confidence 0.43 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0.36 Pain Relevance 0.18
1 induced multiple signaling pathways in chondrocytes but that neither p38-MAPK nor PKA contributed to its stimulating effect on the Ank gene.


Negative_regulation (effect) of Ank in chondrocytes
3) Confidence 0.43 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0 Pain Relevance 0.23

General Comments

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