INT224553

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.68
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 1.62
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ankh) plasma membrane (Ankh) molecular_function (Ankh)
cellular_component (Ankh) biological_process (Ankh)
Anatomy Link Frequency
chondrocytes 1
cartilage 1
Ankh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 252 99.36 Very High Very High Very High
Osteoarthritis 12 96.48 Very High Very High Very High
spinal inflammation 6 85.60 High High
cytokine 6 77.92 Quite High
addiction 6 59.68 Quite High
ketamine 6 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
Immobilon 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 18 99.98 Very High Very High Very High
Chondrocalcinosis 72 98.00 Very High Very High Very High
Osteoarthritis 12 96.48 Very High Very High Very High
Aging 18 90.44 High High
Cleidocranial Dysplasia 6 86.72 High High
Low Back Pain 6 85.60 High High
Arthropathy 6 77.76 Quite High
Calcification 6 67.12 Quite High
Repression 12 5.00 Very Low Very Low Very Low
Ankylosis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
1 in the presence of SB203580, a selective p38-MAPK inhibitor, the increase in Ank mRNA level was not affected (Figure 4b).
Transcription (level) of Ank
1) Confidence 0.68 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0 Pain Relevance 0.07
1 increased both Ank mRNA and ANK protein levels, this induction beginning as early as 6 hours.
Transcription (levels) of ANK protein
2) Confidence 0.68 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0.25 Pain Relevance 0.04
Moreover, chondrocytes and cartilage extracts from patients with CPPD disease express high levels of Ank mRNA [17].
Transcription (express) of Ank in cartilage associated with disease
3) Confidence 0.53 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0.28 Pain Relevance 0.05
More recently, mutations in the 5' untranslated region of Ank mRNA were also correlated with sporadic forms of chondrocalcinosis [3].
Transcription (region) of Ank associated with chondrocalcinosis
4) Confidence 0.53 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0.80 Pain Relevance 0.16
Thus, when cells were pretreated with calphostin C (a broad PKC inhibitor), a strong effect on Ank mRNA expression was observed whereas rottlerin (a PKC?
Transcription (expression) of Ank associated with kinase c
5) Confidence 0.53 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0 Pain Relevance 0.69
Moreover, chondrocytes and cartilage extracts from patients with CPPD disease express high levels of Ank mRNA [17].
Transcription (express) of Ank in chondrocytes associated with disease
6) Confidence 0.18 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246241 Disease Relevance 0.28 Pain Relevance 0.05

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox