INT224579

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 4.23
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Cdkn2d) kinase activity (Cdkn2d) cytoplasm (Cdkn2d)
Anatomy Link Frequency
P19 1
Mouse 1
cardiogenic 1
lungs 1
Cdkn2d (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 3 99.80 Very High Very High Very High
Potency 2 99.42 Very High Very High Very High
Arthritis 30 97.90 Very High Very High Very High
rheumatoid arthritis 87 91.60 High High
Inflammation 53 89.44 High High
cytokine 43 71.32 Quite High
Inflammatory stimuli 1 57.20 Quite High
antagonist 36 44.04 Quite Low
chemokine 12 39.36 Quite Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Embryonal Carcinoma 46 99.98 Very High Very High Very High
INFLAMMATION 55 99.60 Very High Very High Very High
Apoptosis 21 98.72 Very High Very High Very High
Arthritis 23 97.90 Very High Very High Very High
Hyperplasia 16 97.04 Very High Very High Very High
Aging 9 94.52 High High
Rheumatoid Arthritis 87 91.60 High High
Experimental Arthritis 13 86.84 High High
Melanoma 36 85.20 High High
Death 1 82.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further, while expression of p19 was variably decreased in lungs from CCSPrtTA/tetO-Sox17 mice maintained on Dox for 2 days, no differences in the expression of p16 or p27 were observed after expression of Sox17 for 1–3 days (data not shown).
Gene_expression (expression) of p19 in lungs
1) Confidence 0.41 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682659 Disease Relevance 0 Pain Relevance 0
derived from arthritis-susceptible rats is paradoxically associated with reduced levels of pro-inflammatory mediators but high expression of IL-23 (p19), whereas non-susceptible rats show the inverse phenotype.
Gene_expression (expression) of p19 associated with inflammatory mediators and arthritis
2) Confidence 0.06 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246244 Disease Relevance 1.35 Pain Relevance 0.63
In P19 cells expressing GFP under a cardiac-specific promoter to monitor their CM differentiation, NO stimulated guanylate cyclase to produce cGMP, an activator of cGMP-dependent protein kinase G [12].
Gene_expression (expressing) of P19 in P19
3) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964328 Disease Relevance 0.08 Pain Relevance 0
For this purpose, the cardiogenic potency of OT-GKR was studied in EC P19 cells stably expressing the pcDNA3.1/Amp-OT-GKR-IRES/EGFP (green fluorescence) construct (Fig. 4A).
Gene_expression (expressing) of P19 in cardiogenic associated with embryonal carcinoma and potency
4) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964328 Disease Relevance 0.31 Pain Relevance 0.05
Mouse cells deficient in Chd5 due to loss of one copy by Cre-loxP-mediated recombination expressed decreased levels of p53, p16 and p19.
Gene_expression (expressed) of p19 in Mouse
5) Confidence 0.05 Published 2008 Journal BMC Res Notes Section Body Doc Link PMC2564952 Disease Relevance 0.90 Pain Relevance 0
Subsequent experiments showed that Chd5 mediated apoptosis involved p53 and that Chd5 haploinsufficiency led to decreased expression of CDKN2A (p16) and p19 (human p14ARF-alternate-spliced exon 1?
Gene_expression (expression) of p19 associated with apoptosis
6) Confidence 0.05 Published 2008 Journal BMC Res Notes Section Body Doc Link PMC2564952 Disease Relevance 0.80 Pain Relevance 0
Subsequent experiments showed that Chd5 mediated apoptosis involved p53 and that Chd5 haploinsufficiency led to decreased expression of CDKN2A (p16) and p19 (human p14ARF-alternate-spliced exon 1?
Gene_expression (exon) of p19 associated with apoptosis
7) Confidence 0.05 Published 2008 Journal BMC Res Notes Section Body Doc Link PMC2564952 Disease Relevance 0.79 Pain Relevance 0

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