INT224613

Context Info Confidence 0.04 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.90 Pain Relevance 0.40

L1cam (Mus musculus)

Pain Link Frequency Relevance Heat rheumatoid arthritis 104 75.20 cytokine 58 74.76 Osteoarthritis 2 61.52 Arthritis 10 28.80 metalloproteinase 50 5.00 Inflammation 48 5.00 chemokine 10 5.00 methotrexate 8 5.00 COX-2 inhibitor 4 5.00 antagonist 4 5.00

Disease Link Frequency Relevance Heat Cancer 14 85.92 Metastasis 4 84.96 Apoptosis 56 81.28 Rheumatoid Arthritis 104 75.20 Osteoarthritis 2 61.52 Disease 22 31.68 Arthritis 8 28.80 INFLAMMATION 50 5.00 Severe Combined Immunodeficiency 16 5.00 Adhesions 14 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Based on the observation that endogenous retroviral sequences such as L1 can induce specific signalling molecules, including p38?

Positive_regulation (as) of Localization (retroviral) of L1

1) Confidence 0.04 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246247 Disease Relevance 0.45 Pain Relevance 0.20

Based on the observation that endogenous retroviral sequences such as L1 can induce specific signalling molecules, including p38?

Positive_regulation (induce) of Localization (retroviral) of L1

2) Confidence 0.04 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246247 Disease Relevance 0.45 Pain Relevance 0.20

General Comments

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