INT224616

Context Info Confidence 0.13 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.21 Pain Relevance 0.18

phosphatase activity (Pten) mitochondrion (Pten) plasma membrane (Pten) nucleus (Pten) intracellular (Pten) enzyme binding (Pten)

Pten (Mus musculus)

Pain Link Frequency Relevance Heat rheumatoid arthritis 52 99.84 Arthritis 5 61.56 Inflammation 24 59.52 cytokine 29 5.00 metalloproteinase 25 5.00 chemokine 5 5.00 methotrexate 4 5.00 COX-2 inhibitor 2 5.00 antagonist 2 5.00 cINOD 1 5.00

Disease Link Frequency Relevance Heat Rheumatoid Arthritis 52 99.84 Apoptosis 28 97.76 Disease 11 95.80 Cancer 7 68.84 Severe Combined Immunodeficiency 8 64.24 Experimental Arthritis 1 61.56 INFLAMMATION 25 59.52 Adhesions 7 5.00 Hypoxia 4 5.00 Arthritis 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

, which at least partly could be responsible for the diminished levels of PTEN in RA [63].

Regulation (responsible) of Negative_regulation (levels) of PTEN associated with rheumatoid arthritis

1) Confidence 0.13 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246247 Disease Relevance 1.21 Pain Relevance 0.18

General Comments

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