INT224641

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp16) plasma membrane (Mmp16)
Anatomy Link Frequency
synovium 1
Mmp16 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 52 99.84 Very High Very High Very High
metalloproteinase 25 99.44 Very High Very High Very High
cINOD 1 58.08 Quite High
Inflammation 24 53.60 Quite High
COX-2 inhibitor 2 44.00 Quite Low
diclofenac 1 35.68 Quite Low
cytokine 29 22.20 Low Low
chemokine 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 52 99.84 Very High Very High Very High
Severe Combined Immunodeficiency 8 88.56 High High
INFLAMMATION 25 57.84 Quite High
Disease 11 56.56 Quite High
Apoptosis 28 44.72 Quite Low
Malignant Neoplastic Disease 1 41.44 Quite Low
Metastasis 2 39.12 Quite Low
Cancer 7 33.36 Quite Low
Adhesions 7 12.44 Low Low
Hypoxia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MT1-MMP and MT3-MMP are abundant in RA synovium, with MT3-MMP being expressed by RASFs, and MT1-MMP by RASFs and CD68-positive osteoclasts and macrophages.
Localization (abundant) of MT3-MMP in synovium associated with rheumatoid arthritis
1) Confidence 0.13 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246247 Disease Relevance 0.79 Pain Relevance 0.79

General Comments

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